Products for Research Use Only
RegisterLogin

ALK5-IN-6

CAT: 0804-HY-142950Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-142950Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ALK5-IN-6 is a potent inhibitor of ALK5. Transforming growth factor beta (TGF-β) is a multifunctional cytokine that is involved in regulating cell proliferation, differentiation and apoptosis through complex receptor signaling pathways on the cell surface in an autocrine, paracrine and endocrine manner. ALK5-IN-6 has the potential for the research of TGF-β-related diseases and conditions, including but not limited to tumors, fibrotic diseases, inflammatory diseases, autoimmune diseases, etc (extracted from patent WO2021129621A1, compound 1) [1].
CAS Number
2657720-04-0
UNSPSC
12352005
Target
TGF-β Receptor
Type
Reference compound
Related Pathways
TGF-beta/Smad
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/alk5-in-6.html
Solubility
10 mM in DMSO
Smiles
COC1=CC2=C(OC3=CN(C4CC4)N=C3C5CCOCC5)C=CN=C2C=C1OCCCN6CCOCC6
Molecular Formula
C28H36N4O5
Molecular Weight
508.61
References & Citations
[1]Tang Feng, et al. Pyrazoles. Patent WO2021129621A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-151273ALK5-IN-27
HY-142949ALK5-IN-7
HY-163507ALK5-IN-79
HY-151282ALK5-IN-32
HY-162902ALK5-IN-82
HY-168607ALK5-IN-83
HY-178231ALK5-IN-85
HY-151277ALK5-IN-29
HY-144043-01ALK5-IN-8
HY-151279ALK5-IN-30

Alternative Products

CatalogName
T63498-01ALK5-IN-6
103-M96ALK5
BA9089-5.1ALK5-IN-34
BA9158-10ALK5-IN-8
T62394-01ALK5-IN-31
T64051-01ALK5-IN-9
T63114-01ALK5-IN-7
70R-50476ALK5 antibody
MBS5805228ALK5-IN-27
GTR19185980-01ALK5-IN-26

Popular Products