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ALK5-IN-7

CAT: 0804-HY-142949Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-142949Size:1 Each
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Description
ALK5-IN-7 is a potent inhibitor of ALK5. Transforming growth factor beta (TGF-β) is a multifunctional cytokine that is involved in regulating cell proliferation, differentiation and apoptosis through complex receptor signaling pathways on the cell surface in an autocrine, paracrine and endocrine manner. ALK5-IN-7 has the potential for the research of TGF-β-related diseases and conditions, including but not limited to tumors, fibrotic diseases, inflammatory diseases, autoimmune diseases, etc (extracted from patent WO2021129621A1, compound 4) [1].
CAS Number
2657720-07-3
UNSPSC
12352005
Target
TGF-β Receptor
Type
Reference compound
Related Pathways
TGF-beta/Smad
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/alk5-in-7.html
Solubility
10 mM in DMSO
Smiles
OC(C)(C)C1=NC=CC(C2=CC3=NC=CC(OC4=CN(C5CC5)N=C4C6CCOCC6)=C3S2)=C1
Molecular Formula
C26H28N4O3S
Molecular Weight
476.59
References & Citations
[1]Tang Feng, et al. Pyrazoles. Patent WO2021129621A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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