ALK5-IN-31

CAT: 0931-T62394-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T62394-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2785430-87-5
Target
Others|||TGF-beta/Smad
Related Pathways
Others|||Stem Cells
Bioactivity
ALK5-IN-31 is a selective inhibitor of ALK-5 (IC50?10 nM) and also inhibits TGF-?-induced SMAD signalling.ALK5-IN-31 has the potential to inhibit tumour growth in vivo.ALK5-IN-31 can be used in the study of proliferative diseases (e.g. cancer, fibrotic diseases, systemic sclerosis) .
Smiles
N(C=1C2=C(N=NC1)C(C)=CC=C2)C3=NC(NC4=CC(F)=C(C=C4)N5CCNCC5)=NC=C3
Molecular Formula
C23H23FN8
Molecular Weight
430.48
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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