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ALK5-IN-33

CAT: 0804-HY-151283Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-151283Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ALK5-IN-33 (Compound EX-10) is a selective, orally active ALK-5 inhibitor with an IC50 ≤10 nM[1].
CAS Number
2785430-89-7
UNSPSC
12352005
Target
TGF-β Receptor
Type
Reference compound
Related Pathways
TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/alk5-in-33.html
Solubility
10 mM in DMSO
Smiles
CC1=CC=CC2=C(NC3=NC(NC4=CC=C(N5CCOCC5)C=C4)=NC=C3)C=NN=C12
Molecular Formula
C23H23N7O
Molecular Weight
413.48
References & Citations
[1]Bettina FRANZ, et al. Alk-5 inhibitors and uses thereof. Patent WO2022126133A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ALK2; ALK5

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