ALK5-IN-85

• Description :

  ALK5-IN-85 (Compound 19) is a TGFβRI (ALK5) inhibitor with an IC50 [1].

• UNSPSC :

  12352005

• Target :

  TGF-β Receptor

• Related Pathways :

  TGF-beta/Smad

• Field of Research :

  Cancer; Inflammation/Immunology

• Smiles :

  O=C(C1=CC(NC(CN2N=C(C(C3=C4C=CC=CC4=NC=C3)=C2)C5=CC=CC(C)=N5)=O)=CC(F)=C1)OCCN6CCNCC6

• Molecular Formula :

  C33H32FN7O3

• Molecular Weight :

  593.65

• References & Citations :

  [1]BOSSER ARTAL R, et al. 2- (3-pyridin-2-yl-4-quinolin-4-yl-pyrazol-1-yl) -acetamide derivatives as inhibitors of transforming growth factor-beta receptor i/alk5. WO2022069509A1. 2022-04-07.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  ALK5

• CAS Number :

  [2766583-86-0]