ALK5-IN-9

CAT: 0931-T64051-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T64051-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2489611-06-3
Target
Others|||TGF-beta/Smad
Related Pathways
Stem Cells|||Others
Bioactivity
ALK5-IN-9 is a potent, orally active inhibitor of TGF?RI (ALK5) . ALK5-IN-9 inhibits ALK5 autophosphorylation (IC50: 25 nM) and inhibits NIH3T3 cell activity (IC50: 74.6 nM) . ALK5-IN-9 has shown research potential in cancer diseases.
Smiles
O(C=1C(=NN(C1)C2CC2)C3CCOCC3)C=4C=C(NC5=CC(C(F)(F)F)=C(C=C5)N6CCN(CCO)CC6)N=CC4
Molecular Formula
C29H35F3N6O3
Molecular Weight
572.62
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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