ALK5-IN-9

• Target:

  Others|||TGF-beta/Smad

• Related Pathways:

  Stem Cells|||Others

• Bioactivity:

  ALK5-IN-9 is a potent, orally active inhibitor of TGF?RI (ALK5) . ALK5-IN-9 inhibits ALK5 autophosphorylation (IC50: 25 nM) and inhibits NIH3T3 cell activity (IC50: 74.6 nM) . ALK5-IN-9 has shown research potential in cancer diseases.

• Smiles:

  O(C=1C(=NN(C1)C2CC2)C3CCOCC3)C=4C=C(NC5=CC(C(F)(F)F)=C(C=C5)N6CCN(CCO)CC6)N=CC4

• Molecular Formula:

  C29H35F3N6O3

• Molecular Weight:

  572.62

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2489611-06-3