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Gliocidin

CAT: 1568-C03574-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1568-C03574-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
62289-81-0
Synonyms
SW106065
SKU
C03574-5mg
Target
Dehydrogenase
Applications
Metabolism
Additionnal Information
Gliocidin (SW106065), is a nicotinamide-mimetic prodrug that targets glioblastoma cells with an IC50 of 150 nM, by exploiting a de novo purine synthesis vulnerability via indirect inhibition of IMPDH2. It readily crosses the BBB and can be used in the treatment of all malignant brain tumors.

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