ALK5-IN-79

CAT: 0804-HY-163507Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-163507Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
ALK5-IN-79 (compound 57) is an ALK inhibitor with anticancer activity, by blocking TGF-β1/SMAD signaling pathway. ALK5-IN-79 attenuates the production of extracellular matrix (ECM) and deposition of collagen. ALK5-IN-79 exhibits adequate pharmacokinetic (PK) properties and good in vivo tolerance.
CAS Number
[2725056-38-0]
UNSPSC
12352005
Target
Anaplastic lymphoma kinase (ALK)
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/alk5-in-79.html
Solubility
10 mM in DMSO
Smiles
O=C(C)N1CCC(CC1)CCN2N=C(C3=C2N=CN=C3N)C4=CC=C5NC=C(C)C5=C4
Molecular Formula
C23H27N7O
Molecular Weight
417.51
References & Citations
[1]Yubo Wang et al. Design, synthesis and evaluation of a pyrazolo[3,4-d]pyrimidine derivative as a novel and potent TGFβ1R1 inhibitor. European Journal of Medicinal Chemistry. Volume 271, 5 May 2024, 116395
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-151282ALK5-IN-32
HY-162902ALK5-IN-82
HY-142949ALK5-IN-7
HY-142950ALK5-IN-6
HY-151273ALK5-IN-27
HY-178231ALK5-IN-85
HY-151277ALK5-IN-29
HY-168607ALK5-IN-83
HY-151281ALK5-IN-31
HY-151289-01ALK5-IN-34

Alternative Products

CatalogName
MF-0062556-01ALK5-IN-79
103-M96ALK5
MBS5315095-01ALK5 Antibody
MBS5804806ALK5-IN-34
MBS5805082ALK5-IN-31
MBS5805228ALK5-IN-27
MBS5805788ALK5-IN-7
MF-0050877-01ALK5-IN-9
BA9158-10ALK5-IN-8
MBS5804805ALK5-IN-33

Popular Products