NNRT-IN-14

• Description :

  NNRT-IN-14 is an HIV-1 reverse transcriptase inhibitor (IC50 = 0.175 µM) . NNRT-IN-14 can form hydrogen bonds with LYS101, PRO225, and PHE227, and π–π stacking with TYR181 and TRP229. NNRT-IN-14 can be used for the study of HIV[1].

• UNSPSC :

  12352005

• Target :

  HIV; Reverse Transcriptase

• Related Pathways :

  Anti-infection

• Field of Research :

  Infection

• Smiles :

  CC1=C(OC2=C(C=NC=C3)C3=NC(NC4=CC=C(C#N)C=N4)=C2)C(C)=CC(/C=C/C#N)=C1

• Molecular Formula :

  C25H18N6O

• Molecular Weight :

  418.45

• References & Citations :

  [1]Baicharoen A, et al. Discovery and molecular docking studies of nitrogen containing naphthyridine derivatives as potent HIV1 NNRTIs with anticancer potential. Sci Rep. 2025 Oct 1;15 (1) :32622.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  HIV-1