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NNRT-IN-15

CAT: 0013-GTR19274853-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274853-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NNRT-IN-15 (Compound 16 a) is a potent non-nucleoside reverse transcriptase (NNRT) inhibitor. It exhibits an EC50 of 3 nM against wild-type HIV-1 and effectively inhibits seven mutant strains (L100I, K103N, Y181C, etc.) with EC50 values ranging from 8.2 to 43.4 nM. The compound shows low cytotoxicity in MT-4 cells (CC50 = 196.46 μM) and also inhibits wild-type HIV-1RT and hERG channels with IC50 values of 0.7599 μM and 27.455 μM, respectively. NNRT-IN-15 is suitable for HIV-1 infection research.
Storage Conditions
-20°C
Notes
For research use only.

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