NNRT-IN-2

• Target :

  HIV Protease|||Reverse Transcriptase

• Related Pathways :

  Proteases/Proteasome|||Microbiology/Virology

• Bioactivity :

  NNRT-IN-2 (compound 7w) is an orally administered non-nucleoside reverse transcriptase inhibitor (NNRTI) that effectively suppresses both wild-type HIV-1 and various mutant strains. It inhibits HIV-1 reverse transcriptase with an EC 50 value of 22 nM. Additionally, NNRT-IN-2 exhibits insensitivity to CYP and hERG, demonstrating favorable safety and pharmacokinetic profiles [1].

• Smiles :

  O(C1=C(C(F)(F)F)C=CN(CC=2N(C)C(=O)NN2)C1=O)C=3C4=C(C=CC3)C=NC=C4

• Molecular Formula :

  C19H14F3N5O3

• Molecular Weight :

  417.34

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2999794-78-2