NNRT-IN-13

CAT: 0804-HY-178341Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-178341Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
NNRT-IN-13 is a potent non-nucleoside reverse transcriptase (NNRT) inhibitor that directly inhibiting HIV-1 reverse transcriptase (IC₅₀ = 0.25 μM) . NNRT-IN-13 exhibits excellent antiviral activity against wild-type HIV-1 (EC₅₀ = 0.0046 μM) and a broad spectrum of drug-resistant mutants. NNRT-IN-13 exhibits favorable in vivo metabolic and safety profiles. NNRT-IN-13 can be used for human immunodeficiency virus (HIV) research[1].
UNSPSC
12352005
Target
HIV; Reverse Transcriptase
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=S(C1=CC=C(CN2CCC(NC3=NC(OC4=C(C=C(C=C4C)/C=C/C#N)C)=CC(NCC5=COC=N5)=N3)CC2)C=C1)(N)=O
Molecular Formula
C31H34N8O4S
Molecular Weight
614.72
References & Citations
[1]Ji X, et al. Exploring the HIV-1 Reverse Transcriptase p51/p66 Interface: Structure-Based Design and Optimization of Novel 2,4,6-Trisubstituted Pyrimidines as Potent NNRTIs with Improved Resistance Profiles. J Med Chem. 2025 Oct 9;68 (19) :20519-20535.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-175519NNRT-IN-11
HY-162720NNRT-IN-4
HY-149928NNRT-IN-1
HY-178923NNRT-IN-14
HY-174417NNRT-IN-10
HY-174303NNRT-IN-9
HY-172408NNRT-IN-6
HY-163110NNRT-IN-2
HY-169207NNRT-IN-5
HY-149338NNRT-IN-3

Alternative Products

CatalogName
T211185-01NNRT-IN-8
T211267-01NNRT-IN-9
T201040-01NNRT-IN-5
T210051-01NNRT-IN-4
T212521-01NNRT-IN-11
T210761-01NNRT-IN-10
T205661-01NNRT-IN-6
T87027-01NNRT-IN-2
I8435-02EInterleukin 13 (IL-13)
MBS590055-01Interleukin-13 (IL-13)

Popular Products