Nrf2 activator-2

CAT: 0931-T61688-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T61688-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others|||Nrf2
Related Pathways
Others|||Immunology/Inflammation
Bioactivity
Nrf2 activator-2 (referred to as compound O15), an Osthole derivative, is a highly potent Nrf2 agonist exhibiting an EC 50 of 2.9 ?M in 293 T cells. By effectively disrupting the binding between Keap1 and Nrf2, Nrf2 activator-2 activates the Nrf2 pathway. Furthermore, this compound significantly reduces the ubiquitination of Nrf2 in cells, indicating its potential in regulating Nrf2 activity [1].
Molecular Formula
C20H17BrO3
Molecular Weight
385.25
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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