Nrf2 activator-2

• Target :

  Others|||Nrf2

• Related Pathways :

  Others|||Immunology/Inflammation

• Bioactivity :

  Nrf2 activator-2 (referred to as compound O15), an Osthole derivative, is a highly potent Nrf2 agonist exhibiting an EC 50 of 2.9 ?M in 293 T cells. By effectively disrupting the binding between Keap1 and Nrf2, Nrf2 activator-2 activates the Nrf2 pathway. Furthermore, this compound significantly reduces the ubiquitination of Nrf2 in cells, indicating its potential in regulating Nrf2 activity [1].

• Molecular Formula :

  C20H17BrO3

• Molecular Weight :

  385.25

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C