Nrf2 activator-2

• Target:

  Others|||Nrf2

• Related Pathways:

  Others|||Immunology/Inflammation

• Bioactivity:

  Nrf2 activator-2 (referred to as compound O15), an Osthole derivative, is a highly potent Nrf2 agonist exhibiting an EC 50 of 2.9 ?M in 293 T cells. By effectively disrupting the binding between Keap1 and Nrf2, Nrf2 activator-2 activates the Nrf2 pathway. Furthermore, this compound significantly reduces the ubiquitination of Nrf2 in cells, indicating its potential in regulating Nrf2 activity [1].

• Molecular Formula:

  C20H17BrO3

• Molecular Weight:

  385.25

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C