Nrf2 activator-12

• Target:

  Nrf2

• Related Pathways:

  Immunology/Inflammation

• Bioactivity:

  Nrf2 activator-12 (compound 10v) effectively activates Nrf2 (EC50=83.5 nM) and exhibits favorable pharmacological properties. It reverses disease progression and alleviates demyelination in a mouse model of experimental autoimmune encephalomyelitis.

• Smiles:

  S (/C=C/C1=C (Cl) C=CC=C1) (=N) (=O) C2=C (Cl) C=CC=N2

• Molecular Formula:

  C13H10Cl2N2OS

• Molecular Weight:

  313.2

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3020661-05-3