Nrf2 activator 17

• Target:

  Nrf2|||Serotonin Transporter

• Related Pathways:

  Immunology/Inflammation|||Neuroscience

• Bioactivity:

  Nrf2 activator 17 (compound 10) is an Nrf2 agonist that inhibits the interaction between Keap1 and Nrf2 with an IC50 value of <0.1 pM. In HepG2 cells, it demonstrates an EC50 of <10 ?M.

• Smiles:

  O=C(O)CC1C2=CC=C3C(=C2)CN(C(=O)N4CCC(OCCCCN5N=NC=6C5=CC=C1C6C)CC4)CC3

• Molecular Formula:

  C29H35N5O4

• Molecular Weight:

  517.62

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3059044-55-9