Nrf2-Activator-12G

• UNSPSC Description:

  Nrf2-Activator-12G (compd 12g) is an activator of Nrf2. Nrf2-Activator-12G induces the expression of nrf2-dependentantioxidant enzymes at both mRNA and protein levels in DAergic neuronal cell. Nrf2-Activator-12G can used in study Parkinson’s Disease[1].

• Target Antigen:

  Keap1-Nrf2

• Type:

  Reference compound

• Related Pathways:

  NF-κB

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/nrf2-activator-12g.html

• Purity:

  99.61

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=S(/C=C/C1=CC=CC=C1Cl)(C2=CC=CC=C2OC)=O

• Molecular Weight:

  308.78

• References & Citations:

  [1]Woo SY, et al. Discovery of vinyl sulfones as a novel class of neuroprotective agents toward Parkinson's disease therapy. J Med Chem. 2014 Feb 27;57(4):1473-87.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1554271-18-9