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Nrf2 activator 18

CAT: 0931-T203243-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203243-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Others, Nrf2
Related Pathways
Others, Immunology/Inflammation
Bioactivity
Nrf2 activator 18 (Compound 11a) is an orally active activator of the Keap1/Nrf2/HO-1 signaling pathway, promoting Nrf2 nuclear translocation and enhancing antioxidant effects. It inhibits IL-6 release with an IC50 of 4.816 μM. In a mouse model of PM2.5-induced lung injury, Nrf2 activator 18 demonstrates anti-inflammatory activity.
Molecular Formula
C23H24FN3O
Molecular Weight
377.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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