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Nrf2/HO-1 activator 2

CAT: 0931-T61522-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61522-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Akt, Reactive Oxygen Species, ERK, JNK, Nrf2, Others
Related Pathways
PI3K/Akt/mTOR signaling, Metabolism, MAPK, Cytoskeletal Signaling, Others, Immunology/Inflammation, NF-κB
Bioactivity
Nrf2/HO-1 activator 2 (compound 13m), a difluoro-substituted derivative, is a highly potent activator of Nrf2/HO-1 with substantial neuroprotective and antioxidant properties. It functions by activating the Nrf2/HO-1 pathway through the phosphorylation of ERK1/2, JNK, or Akt in PC12 cells and is useful in investigating Parkinson's disease (PD) [1].
Molecular Formula
C20H16F2O5
Molecular Weight
374.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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