Nrf2 activator-11

Nrf2 activator-11

• UNSPSC Description: Nrf2 activator-11 (compound M11) is a Nrf2 activator with blood-brain permeability. Nrf2 activator-11 has anti-oxidation, anti-inflammation, anti-ferroptosis and anti-apoptosis. Nrf2 activator-11 can be used to study cerebral  ischemia-reperfusion (CI/R) injury models[1].
• Target Antigen: Apoptosis; Keap1-Nrf2
• Type: Reference compound
• Related Pathways: Apoptosis;NF-κB
• Field of Research: Inflammation/Immunology; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/nrf2-activator-11.html
• Smiles: O=C(C1=C(O)C=C(C)C=C1)NCCC2=CNC3=CC=C(N(C)C)C=C32
• Molecular Weight: 337.42
• References & Citations: [1]Wu G, et al. Design, synthesis and biological evaluation of N-salicyloyl tryptamine derivatives as multifunctional neuroprotectants for the treatment of ischemic stroke. Eur J Med Chem. 2024 Nov 15;278:116795.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported