Nrf2 activator-11

• UNSPSC Description:

  Nrf2 activator-11 (compound M11) is a Nrf2 activator with blood-brain permeability. Nrf2 activator-11 has anti-oxidation, anti-inflammation, anti-ferroptosis and anti-apoptosis. Nrf2 activator-11 can be used to study cerebral  ischemia-reperfusion (CI/R) injury models[1].

• Target Antigen:

  Apoptosis; Keap1-Nrf2

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;NF-κB

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/nrf2-activator-11.html

• Smiles:

  O=C(C1=C(O)C=C(C)C=C1)NCCC2=CNC3=CC=C(N(C)C)C=C32

• Molecular Weight:

  337.42

• References & Citations:

  [1]Wu G, et al. Design, synthesis and biological evaluation of N-salicyloyl tryptamine derivatives as multifunctional neuroprotectants for the treatment of ischemic stroke. Eur J Med Chem. 2024 Nov 15;278:116795.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported