Nrf2 activator-22

• Description :

  Nrf2 activator-22, a Nrf2 activator, is a PROTAC target protein ligand (Ligands for Target Protein for PROTAC) . Nrf2 activator-22 can be used for synthesis PROTAC K-Ras Degrader-7 (HY-178873) [1].

• UNSPSC :

  12352005

• Target :

  Keap1-Nrf2; Ligands for Target Protein for PROTAC

• Related Pathways :

  NF-κB; PROTAC

• Field of Research :

  Cancer

• Smiles :

  OC1=C2C(N=NN2C)=CC(C(C3=CC(CN4S(=O)(C5=CC=CC=C5O[C@@H](C4)C)=O)=C(C=C3)C)CC(O)=O)=C1

• Molecular Formula :

  C27H28N4O6S

• Molecular Weight :

  536.60

• References & Citations :

  [1]Austin J, et al. PROTAC Compounds Binding Keap1 Ubiquitin Ligase for Targeted Protein Degradation. WO2025085815A1. 2025-04-24.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [3082764-64-2]