Nrf2 activator-22

• Description:

  Nrf2 activator-22, a Nrf2 activator, is a PROTAC target protein ligand (Ligands for Target Protein for PROTAC) . Nrf2 activator-22 can be used for synthesis PROTAC K-Ras Degrader-7 (HY-178873) [1].

• UNSPSC:

  12352005

• Target:

  Keap1-Nrf2; Ligands for Target Protein for PROTAC

• Related Pathways:

  NF-κB; PROTAC

• Field of Research:

  Cancer

• Smiles:

  OC1=C2C (N=NN2C) =CC (C (C3=CC (CN4S (=O) (C5=CC=CC=C5O[C@@H] (C4) C) =O) =C (C=C3) C) CC (O) =O) =C1

• Molecular Formula:

  C27H28N4O6S

• Molecular Weight:

  536.60

• References & Citations:

  [1]Austin J, et al. PROTAC Compounds Binding Keap1 Ubiquitin Ligase for Targeted Protein Degradation. WO2025085815A1. 2025-04-24.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  3082764-64-2