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IDO1/TDO-IN-9

CAT: 0804-HY-177086-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-177086-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IDO1/TDO-IN-9 (Compound 66) is a potent dual inhibitor targeting indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO) with IC50s of [1].
CAS Number
1878200-88-4
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.54
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC1=NOC2=NC(Cl)=C(F)C=C21
Molecular Formula
C6H3ClFN3O
Molecular Weight
187.56
References & Citations
[1]Brian Desmond Palmer, et al. Inhibitors of tryptophan dioxygenases (ido1 and tdo) and their use in therapy. WO2016024233A1. 2016-02-18.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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