IDO1/TDO-IN-9

• Description:

  IDO1/TDO-IN-9 (Compound 66) is a potent dual inhibitor targeting indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO) with IC50s of [1].

• UNSPSC:

  12352005

• Target:

  Indoleamine 2,3-Dioxygenase (IDO)

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Purity:

  99.54

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  NC1=NOC2=NC (Cl) =C (F) C=C21

• Molecular Formula:

  C6H3ClFN3O

• Molecular Weight:

  187.56

• References & Citations:

  [1]Brian Desmond Palmer, et al. Inhibitors of tryptophan dioxygenases (ido1 and tdo) and their use in therapy. WO2016024233A1. 2016-02-18.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1878200-88-4