Products for Research Use Only
RegisterLogin

IDO1/TDO-IN-4

CAT: 0804-HY-151108-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-151108-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
IDO1/TDO-IN-4 is a potent IDO1/TDO dual inhibitor, with IC50 values of 3.53 μM (IDO1) and 1.15 μM (TDO) . IDO1/TDO-IN-4 forms hydrogen bond with IDO1, and π π stacking interaction with TDO. IDO1/TDO-IN-4 can be used in the research of depression, and depression-induced infectious, metabolic, and autoimmune disorders[1].
CAS Number
461424-21-5
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ido1-tdo-in-4.html
Purity
99.74
Solubility
DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C) |Methanol : 16.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C12=CC=CC=C1NC3=C2C=CN=C3C4=CNC=N4
Molecular Formula
C14H10N4
Molecular Weight
234.26
References & Citations
[1]Yu Zhang, et al. B Discovery of 1- (Hetero) aryl-β-carboline Derivatives as IDO1/TDO Dual Inhibitors with Antidepressant Activity. J Med Chem. 2022 Aug 7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IDO1

Related Products

CatalogName
HY-162962IDO1/TDO-IN-7
HY-177086-01IDO1/TDO-IN-9
HY-146673IDO1/TDO-IN-2
HY-149411IDO1/TDO-IN-6
HY-173513IDO1/TDO-IN-8
HY-146674IDO1/TDO-IN-3
HY-144778IDO1/TDO-IN-1
HY-178470IDO1/TDO-IN-10
HY-128355-01IDO/TDO-IN-1
HY-128355A-01(R) -IDO/TDO-IN-1

Alternative Products

CatalogName
T60318-01IDO1/TDO-IN-4
T200785-01IDO1/TDO-IN-7
T61385-01IDO1/TDO-IN-1
T207127-01IDO1/TDO-IN-8
T60499-01IDO1/TDO-IN-2
MBS5820457IDO1/TDO-IN-6
GTR19187421-01IDO1/TDO-IN-3
GTR19273626-01IDO1/TDO-IN-10
T211673-01IDO1/TDO-IN-9
72035Universal IDO1/IDO2/TDO Inhibitor Screening Assay Kit

Popular Products