IDO1/TDO-IN-4

• Target:

  Indoleamine 2,3-Dioxygenase (IDO) |||IDO

• Related Pathways:

  Metabolism

• Purity:

  0.9888

• Bioactivity:

  IDO1/TDO-IN-4 is a novel dual inhibitor of IDO1/TDO with antidepressant activity, forming hydrogen bonds with IDO1 and ?-? stacking interactions with TDO. IDO1/TDO-IN-4 rescues lipopolysaccharide-induced depressive-like behaviors in mice, used for cancer and Alzheimer's disease research.

• Smiles:

  N1=CNC (=C1) C=2N=CC=C3C4=CC=CC=C4NC23

• Molecular Formula:

  C14H10N4

• Molecular Weight:

  234.26

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  461424-21-5