ALK5-IN-79

• Target:

  ALK

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Angiogenesis

• Bioactivity:

  ALK5-IN-79 (compound 57), an ALK inhibitor, exhibits anticancer activity by inhibiting the TGF-?1/SMAD signaling pathway. It effectively reduces the production of extracellular matrix (ECM) and collagen deposition. Moreover, ALK5-IN-79 demonstrates satisfactory pharmacokinetic (PK) properties and favorable in vivo tolerance.

• Smiles:

  O=C (N1CCC (CCN2N=C (C3=CC=C4NC=C (C4=C3) C) C=5C (=NC=NC52) N) CC1) C

• Molecular Formula:

  C23H27N7O

• Molecular Weight:

  417.51

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2725056-38-0