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ALK5-IN-79

CAT: 0931-T85628-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T85628-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2725056-38-0
Target
ALK
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
ALK5-IN-79 (compound 57), an ALK inhibitor, exhibits anticancer activity by inhibiting the TGF-β1/SMAD signaling pathway. It effectively reduces the production of extracellular matrix (ECM) and collagen deposition. Moreover, ALK5-IN-79 demonstrates satisfactory pharmacokinetic (PK) properties and favorable in vivo tolerance.
Smiles
O=C(N1CCC(CCN2N=C(C3=CC=C4NC=C(C4=C3)C)C=5C(=NC=NC52)N)CC1)C
Molecular Formula
C23H27N7O
Molecular Weight
417.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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