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ALK5-IN-28

CAT: 0931-T62302-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T62302-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2785430-84-2
Target
Others|||TGF-beta/Smad
Related Pathways
Stem Cells|||Others
Bioactivity
ALK5-IN-28 is a selective inhibitor of ALK-5 with an IC50 ? 10 nM that inhibits TGF-?-induced SMAD signalling.ALK5-IN-28 has the potential to inhibit tumour growth in vivo.ALK5-IN-28 can be used to study proliferative diseases (e.g. cancer, fibrotic diseases, systemic sclerosis) .
Smiles
N(C=1C2=C(C(C)=CC=C2)N=NC1)C3=NC(NC4=CC=C(CC5CCNCC5)C=C4)=NC=C3
Molecular Formula
C25H27N7
Molecular Weight
425.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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