ALK5-IN-28

• Target:

  Others|||TGF-beta/Smad

• Related Pathways:

  Stem Cells|||Others

• Bioactivity:

  ALK5-IN-28 is a selective inhibitor of ALK-5 with an IC50 ? 10 nM that inhibits TGF-?-induced SMAD signalling.ALK5-IN-28 has the potential to inhibit tumour growth in vivo.ALK5-IN-28 can be used to study proliferative diseases (e.g. cancer, fibrotic diseases, systemic sclerosis) .

• Smiles:

  N(C=1C2=C(C(C)=CC=C2)N=NC1)C3=NC(NC4=CC=C(CC5CCNCC5)C=C4)=NC=C3

• Molecular Formula:

  C25H27N7

• Molecular Weight:

  425.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2785430-84-2