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PDE4-IN-26

CAT: 0931-T205303-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205303-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
P38 MAPK, PDE
Related Pathways
MAPK, Metabolism
Bioactivity
PDE4-IN-26 (Compound A5) is an orally active, highly selective inhibitor of PDE4. It exhibits anti-inflammatory properties by inhibiting p38 MAPK phosphorylation. In mouse models of acute lung injury and chronic obstructive pulmonary disease, PDE4-IN-26 reduces lung inflammation, damage, and fibrosis, while promoting sputum secretion and alleviating cough. It is useful for researching lung injury-related diseases.
Molecular Formula
C22H18F2N4O3S
Molecular Weight
456.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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