PDE4-IN-16

• UNSPSC Description:

  PDE4-IN-16 (compound 27) is a PDE4 inhibitor with an IC50 value of 3.61 μM. PDE4-IN-16 can be used for the research of inflammatory diseases and central nervous system (CNS) disorders involving elevated levels of cytokines[1].

• Target Antigen:

  Phosphodiesterase (PDE)

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/pde4-in-16.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=C(C(F)(F)F)N(C2=CC=C(N)C=C2)N=C1)OCC

• Molecular Weight:

  299.25

• References & Citations:

  [1]Timothy J. Martins, et al. Pyrazole cyclic amp-specific pde inhibitors. .U.S. WO2001046172, 2001-06-28.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  223500-15-0