PDE4-IN-9

• Target :

  Others|||PDE

• Related Pathways :

  Metabolism|||Others

• Bioactivity :

  PDE4-IN-9 (Compound 5j) is a potent PDE4 inhibitor with an IC50 value of 1.4 ?M against PDE4 in vitro enzyme assays, which is lower than the 2.0 ?M of parent rolipram, and demonstrates good in vivo activity in LPS-induced animal models of asthma/COPD and sepsis [1].

• Smiles :

  C(=O)(C=1N=C(OC1)C2=CC=C(OC)C=C2)N3\C(=N\C#N)\SCC3

• Molecular Formula :

  C15H12N4O3S

• Molecular Weight :

  328.35

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2519450-32-7