PDE4-IN-8

• Target:

  Others|||Interleukin|||PDE

• Related Pathways:

  Immunology/Inflammation|||Metabolism|||Others

• Bioactivity:

  PDE4-IN-8 (Example 5) is a potent Phosphodiesterase 4 (PDE4) inhibitor with an IC50 value of 0.93 nM for PDE4B2. However, it has minimal effects on IL13, IL4, and IFNy, with IC50 values of 4.04 nM, 36.33 nM, and 2394 nM, respectively [1].

• Smiles:

  O(CCC)C=1C=C(C=CC1OC)C=2C=C(C=NC2)[C@@H]3CB(O)OC3

• Molecular Formula:

  C18H22BNO4

• Molecular Weight:

  327.18

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2415085-45-7