PDE4-IN-8

CAT: 0931-MF-0138068-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0138068-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2415085-45-7
Target
Others|||Interleukin|||PDE
Related Pathways
Immunology/Inflammation|||Metabolism|||Others
Bioactivity
PDE4-IN-8 (Example 5) is a potent Phosphodiesterase 4 (PDE4) inhibitor with an IC50 value of 0.93 nM for PDE4B2. However, it has minimal effects on IL13, IL4, and IFNy, with IC50 values of 4.04 nM, 36.33 nM, and 2394 nM, respectively [1].
Smiles
O(CCC)C=1C=C(C=CC1OC)C=2C=C(C=NC2)[C@@H]3CB(O)OC3
Molecular Formula
C18H22BNO4
Molecular Weight
327.18
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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