Products for Research Use Only
RegisterLogin

PDE4-IN-17

CAT: 0804-HY-162583Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-162583Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PDE4-IN-17 (compound 4e) is a potent PDE4 inhibitor. PDE4-IN-17 inhibits PDE4B and PDE4D with IC50s of 10.0 and 15.2 nM, respectively. PDE4-IN-17 has good oral bioavailability (F=66%) and longer half-life (t1/2=2.0 h) in SD rats[1].
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pde4-in-17.html
Smiles
O=C(CN1C=CN=C1)C2=CC=C(OC)C3=C2C=C(C4CC4)O3
Molecular Formula
C17H16N2O3
Molecular Weight
296.32
References & Citations
[1]Xia C, et al. Discovery of 7-alkoxybenzofurans as PDE4 inhibitors with hepatoprotective activity in D-GalN/LPS-induced hepatic sepsis. Eur J Med Chem. 2024 Jun 7;275:116576.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-155692PDE4-IN-13
HY-144684PDE4-IN-8
HY-159654PDE4-IN-19
HY-169981PDE4-IN-24
HY-132887PDE4-IN-3
HY-151174PDE4-IN-12
HY-161381PDE4-IN-15
HY-115871PDE4-IN-4
HY-179639PDE4-IN-30
HY-W787896-01PDE4-IN-25

Alternative Products

CatalogName
T210238-01PDE4-IN-17
BA8215-10PDE4-IN-14
T211159-01PDE4-IN-29
T210960-01PDE4-IN-28
T200132-01PDE4-IN-19
T62969-01PDE4-IN-6
T60934-01PDE4-IN-9
T63912-01PDE4-IN-12
T50023-01PDE4-IN-20
T61295-01PDE4-IN-5

Popular Products