PDE4-IN-3

PDE4-IN-3

• CAS Number: 2755687-49-9
• UNSPSC Description: PDE4-IN-3 is a novel and orally active PDE4 inhibitor with potent inhibitory affinity (IC50 = 4.2 nM).
• Target Antigen: Phosphodiesterase (PDE)
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/pde4-in-3.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C2=C(OC3=CC(OCC4=CC=C(C=C4)F)=C(C(C/C=C(C)\C)=C31)OC)C=C5OC(C)(C=CC5=C2OC/C=C/C(O)=O)C
• Molecular Weight: 600.63
• References & Citations: [1]Huang YY, et al. Mangostanin Derivatives as Novel and Orally Active Phosphodiesterase 4 Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis with Improved Safety. J Med Chem. 2021 Sep 23;64(18):13736-13751.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported