ALK5-IN-8

CAT: 0931-T61203-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T61203-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2705900-81-6

Target

Others, TGF-beta/Smad

Related Pathways

Others, Stem Cells

Bioactivity

ALK5-IN-8 is a highly effective inhibitor of TGFβRI (ALK5) . It hinders the phosphorylation of ALK5 on downstream signaling proteins (Smad2 or Smad3) by obstructing the interaction between TGFβRI and ligands. Consequently, it disrupts or prevents TGF-β signaling. ALK5-IN-8 shows promise in the study of diverse diseases associated with ALK5-mediated pathways[1].

Smiles

C(OCC)(=O)C1=C2N(N=C1)C=CC(=C2)C=3C(=NNC3)C4=CC=C(F)C=C4

Molecular Formula

C19H15FN4O2

Molecular Weight

350.35

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
BA9158-10	ALK5-IN-8
103-M96	ALK5
BA9089-5.1	ALK5-IN-34
HY-151273	ALK5-IN-27
HY-142949	ALK5-IN-7
HY-163507	ALK5-IN-79
HY-151282	ALK5-IN-32
HY-162902	ALK5-IN-82
70R-50476	ALK5 antibody
HY-142950	ALK5-IN-6

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