PPARγ agonist 12
CAT:
804-HY-162320
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PPARγ agonist 12
- UNSPSC Description: PPARγ agonist 12 (compound 9i) is a potent and selective PPARγ agonist with EC50s of 3.98 and 15.42 μM against PPARγ and PPARδ, respectively. PPARγ agonist 12 improves insulin secretion and has anti-diabetic effect[1].
- Target Antigen: PPAR
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/pparγ-agonist-12.html
- Solubility: 10 mM in DMSO
- Smiles: O=S(C1=CC=C(NC2=NC(/C(S2)=C\C3=CC(OC)=C(OCC4=CC(OC)=CC=C4)C=C3)=O)C=C1)(N)=O
- Molecular Weight: 525.60
- References & Citations: [1]Ali I H, et al. Novel thiazolidin-4-one benzenesulfonamide hybrids as PPARγ agonists: Design, synthesis and In vivo anti-diabetic evaluation[J]. European Journal of Medicinal Chemistry, 2024: 116279.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported