PPAR?/? agonist 3

• Target :

  PPAR

• Related Pathways :

  DNA Damage/DNA Repair|||Metabolism

• Bioactivity :

  PPAR?/? agonist 3 (Compound 8) is an orally active PPAR agonist capable of activating PPAR?, PPAR?, and PPAR?, with EC50 values of 5.6 nM, 3.4 nM, and 1278 nM, respectively. It exhibits anti-cholestatic activity in mouse models of cholestatic liver disease induced by ANIT or CDCA.

• Smiles :

  O=C(O)C(OC=1C(=CC(=CC1C)CN2C(=O)N(C3=CC=C(C=C3)C(F)(F)F)CC2)C)(C)C

• Molecular Formula :

  C23H25F3N2O4

• Molecular Weight :

  450.451

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3050611-33-8