PPARδ agonist 9

CAT: 0804-HY-149429Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-149429Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
PPARδ agonist 9 (compound 21) is a PPAR�� agonist (EC50: 3.6 nM) . PPARδ agonist 9 has in vivo efficacy, reducing serum levels of MCP-1 in mice and significantly inhibiting atherosclerosis progression in the LDLr-KO model (inhibition rate: 50-60%) [1].
CAS Number
[928023-21-6]
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pparδ-agonist-9.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC(CC(O)=O)=CC(OCCC2(N3CCCC3)CCN(C4=NC5=CC=C(N=C5S4)C(F)(F)F)CC2)=C1
Molecular Formula
C26H28ClF3N4O3S
Molecular Weight
569.04
References & Citations
[1]Kato T, et al. Design, Synthesis, and Anti-Inflammatory Evaluation of a Novel PPARδ Agonist with a 4- (1-Pyrrolidinyl) piperidine Structure. J Med Chem. 2023 Aug 24;66 (16) :11428-11446..
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-178447PPARγ agonist 20
HY-174278PPARδ agonist 12
HY-173166PPARγ agonist 17
HY-159944PPARγ agonist 14
HY-146742PPARγ agonist 2
HY-121542-01PPARδ agonist 10
HY-162123PPARα/δ agonist 2
HY-162578PPARα/γ agonist 4
HY-159146PPARα agonist 4
HY-139177-01PPARα agonist 2

Alternative Products

CatalogName
T12527-01PPARδ agonist
T209427-01PPAR? agonist 12
T205373-01PPAR?/? agonist 3
T206549-01PPAR? agonist 5
T203583-01PPAR? agonist 15
T89021-01PPAR?/? agonist 4
T61465-01PPAR? agonist 3
T63514-01PPARγ agonist 1
T60535-01PPAR?/? agonist 1
T61417-01PPAR? agonist 7

Popular Products