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PPARα agonist 5

CAT: 0931-T206549-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206549-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Phosphatase, PPAR
Related Pathways
DNA Damage/DNA Repair, Metabolism
Bioactivity
PPARα agonist5 is an orally active, selective partial agonist of PPARα with an EC50 of 3 nM. It reduces lipid accumulation and upregulates PPARα target genes, exhibiting anti-hepatic steatosis properties. Additionally, PPARα agonist5 demonstrates significant lipid-lowering and glucose-lowering effects through partial PPARγ agonist activity and mild inhibition of protein tyrosine phosphatase 1B (PTP1B) with an IC50 of 79.1 μM. It has favorable safety and is applicable in the study of dyslipidemia in type 2 diabetes.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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