Products for Research Use Only
RegisterLogin

PPARδ agonist 10

CAT: 0804-HY-121542-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-121542-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PPARδ agonist 10 (compound 7) is an orally active, selective, and partial agonist of PPARδ, with EC50 values of 0.053 μM and 0.30 µM for hPPARδ (LBD) -GAL4 and mPPARδ, respectively. PPARδ agonist 10 is a partial PPARδ agonist in transactivation assay but a full agonist on free fatty acids (FFA) oxidation in muscle cells both in vitro and in vivo. PPARδ agonist 10 can be used for dyslipidemia research[1].
CAS Number
685139-10-0
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pparδ-agonist-10.html
Solubility
10 mM in Ethanol
Smiles
O=C(COC1=CC=C(C=C1Cl)SC/C=C(C2=CC=C(C=C2)Br)/C3=CC=C(C=C3)Br)O
Molecular Formula
C23H17Br2ClO3S
Molecular Weight
568.71
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Sauerberg P, et al. Identification and synthesis of a novel selective partial PPARdelta agonist with full efficacy on lipid metabolism in vitro and in vivo. J Med Chem. 2007 Apr 5;50 (7) :1495-503.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PPARδ

Related Products

CatalogName
HY-173217PPARα agonist 5
HY-119197-01PPARα/γ/δ agonist 1
HY-178958PPAR agonist 7
HY-176214PPARγ agonist 19
HY-168485PPARα/δ agonist 3
HY-168719PPARγ agonist 16
HY-162963PPARδ agonist 11
HY-146438PPARγ agonist 3
HY-U00340-01PPAR agonist 1
HY-162122PPARα/γ agonist 3

Alternative Products

CatalogName
T12527-01PPARδ agonist
T210601-01PPARδ agonist 12
T209226-01PPARδ agonist 10
T206860-01PPAR agonist 6
T89149-01PPARα agonist 3
T62266-01PPARα agonist 1
T61417-01PPARγ agonist 7
T60535-01PPARα/γ agonist 1
GTR19241063-01PPARγ agonist 15
GTR19230651-01PPARγ agonist 8

Popular Products