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Antitumor agent-135

CAT: 0804-HY-157564Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157564Size:1 Each
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Description
Antitumor agent-135 (Compound 13) is a potent antitumor agent. Antitumor agent-135 induces cell apoptosis, with IC50s of 3.79 , 10.55, 1.14, and 4.14 μM for NSCLC cell lines (A549, H460, PC-9, and PC-9/GR) [1].
CAS Number
2922110-00-5
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-135.html
Solubility
10 mM in DMSO
Smiles
[H][C@@]12C3=C(C4=CC(OC(N(CCN(C(OCC5=C(N(C6=C5C(C(OC)=CC6=O)=O)CC(NCCOCCOCCOCCN7C=C(N=N7)C8=CC(NC9=NC=NC%10=CC(OCCOC)=C(C=C%109)OCCOC)=CC=C8)=O)C)=O)C)C)=O)=CC=C4N3)CCN1C(C%11=CC=CC=C%11N2C)=O
Molecular Formula
C68H77N13O16
Molecular Weight
1332.42
References & Citations
[1]Wei B, et al. Design, synthesis and bioactivity evaluation of the combination of evodiamine and erlotinib linked by indolequinone. Bioorg Med Chem Lett. 2024 Jan 18;99:129619.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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