Antitumor agent-84

• UNSPSC Description:

  Antitumor agent-84 (compound 21a) is a G-quadruplex (G4)-ligand with the ability to stabilize different G4-DNA structures. Antitumor agent-84 has highly effective anti-tumor properties[1].

• Target Antigen:

  G-quadruplex

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/antitumor-agent-84.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=CC(NCCCN2CCCC2)=NC(NC3=NC4=C5CCCC5=CC=C4C(C)=N3)=N1

• Molecular Weight:

  417.55

• References & Citations:

  [1]Bhuma N, et al. The effect of side chain variations on quinazoline-pyrimidine G-quadruplex DNA ligands. Eur J Med Chem. 2023 Feb 15;248:115103.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4