Products for Research Use Only
RegisterLogin

Antitumor agent-200

CAT: 0931-T206452-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T206452-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
3046118-64-0
Target
Microtubule Associated, P-gp
Related Pathways
Cytoskeletal Signaling, Neuroscience, Membrane transporter/Ion channel
Bioactivity
Antitumor agent-200 (Compound 2g) is a microtubule synthesis inhibitor that binds to the colchicine site on tubulin, causing G2/M cell cycle arrest and inducing reactive oxygen species (ROS) production. It demonstrates significant inhibitory activity against P-glycoprotein (P-gp) overexpressing cell lines MCF7/ADR and KBV200, with resistance indices (DRI) of 0.83 and 0.58, respectively. In an MCF-7 xenograft model, Antitumor agent-200 (at 25 mg/kg, administered intraperitoneally) achieves a 57.2% tumor growth inhibition rate. This compound is applicable for research in the field of cancer therapy.
Smiles
O=C(NCC1=CC=C([Se]C)C(O)=C1)C2=CC(F)=CC=C2N3CCOCC3
Molecular Formula
C19H21FN2O3Se
Molecular Weight
423.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T10342-01Antitumor agent-2
T211211-01Antitumor agent-203
T209984-01Antitumor agent-156
T209806-01Antitumor agent-151
T209096-01Antitumor agent-131
T205444-01Antitumor agent-198
T200846-01Antitumor agent-188
T89076-01Antitumor agent-175
T88732-01Antitumor agent-164
T61806-01Antitumor agent-44

Alternative Products

CatalogName
GTR19258802-01Antitumor agent-200
M26058-01Antitumor agent-19
HY-162128Antitumor agent-130
HY-161425Antitumor agent-149
HY-155034Antitumor agent-102
HY-151292Antitumor agent-74
HY-116447-01Antitumor agent-159
HY-149717Antitumor agent-122
HY-115948Antitumor agent-46
HY-152537Antitumor agent-84

Popular Products