Antitumor agent-59

• Description:

  Antitumor agent-59 (Compound 13b) is a potent antitumor agent. Antitumor agent-59 effectively inhibits the proliferation and migration of HCT116 cells. Antitumor agent-59 induces HCT116 cell apoptosis and arrests the cell cycle at the G2/M phase[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/antitumor-agent-59.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CN1C2=C(C(N3CCC4=C(C13)NC5=CC=C(C=C54)OC(CCCC(OC6=CC=C7NC8=C(C7=C6)CCN9C(C%10=C(N(C89)C)C=CC(F)=C%10)=O)=O)=O)=O)C=C(C=C2)F

• Molecular Formula:

  C43H36F2N6O6

• Molecular Weight:

  770.78

• References & Citations:

  [1]Liang H, et al. Discovery of novel bis-evodiamine derivatives with potent antitumor activity. Bioorg Med Chem. 2022 Jul 1;65:116793.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2409952-04-9