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Antitumor agent-114

CAT: 0804-HY-155109Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-155109Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Antitumor agent-114 is a potent stimulator of interferon genes (STING) agonist. Antitumor agent-114 activates immunity and reduces tumor volume in a mouse model of breast cancer. Antitumor agent-114 can be used for immunity and cancer diseases research[1].
CAS Number
2757762-91-5
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-114.html
Solubility
10 mM in DMSO
Smiles
NC1=NC=NC2=C1N=CN2[C@@H]3O[C@H](COP4(OCOC(C5(C)CCCCC5)=O)=O)[C@@H](OP(OCOC(C6(C)CCCCC6)=O)(C=C[C@@H]7[C@@H](O4)[C@@H](F)[C@H](N8C(N=CN=C9N)=C9N=C8)O7)=O)[C@H]3F
Molecular Formula
C39H50F2N10O13P2
Molecular Weight
966.82
References & Citations
[1]Dejmek M, et al. Vinylphosphonate-based cyclic dinucleotides enhance STING-mediated cancer immunotherapy. Eur J Med Chem. 2023 Nov 5;259:115685.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported