PDE4-IN-11

PDE4-IN-11

• CAS Number: 524734-30-3
• UNSPSC Description: PDE4-IN-11 is an inhibitor of phosphodiesterase isoenzyme 4 (PDE4). PDE4-IN-11 displays highly effective bronchodilatory and anti-inflammatory properties, can be used for obstructive or inflammatory airway diseases research[1][2][3].
• Target Antigen: Phosphodiesterase (PDE)
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/pde4-in-11.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1CCC(CC1)C2=CC3=C(N=CC=C3)C(C4=CC=CC(F)=C4)=N2)O
• Molecular Weight: 350.39
• References & Citations: [1]Denholm A, et al. Preparation of naphthyridines as phosphodiesterase isoenzyme 4 (PDE4) inhibitors: World Intellectual Property Organization, WO2003039544[P]. 2003-05-15.|[2]McCarthy C, et al. Use of naphthyridine derivatives as medicaments for the treatment of pulmonary hypertension: World Intellectual Property Organization, WO2007088019[P]. 2007-08-09. |[3]Press NJ, et al. Organic compounds for treating pulmonary hypertension: World Intellectual Property Organization, WO2009013286. 2009-01-29.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported