ER degrader 5

• CAS Number:

  2913192-47-7

• UNSPSC Description:

  ER degrader 5 is a potent estrogen receptor (ER) degrader. ER degrader 5 shows anti-proliferation activity. ER degrader 5 can be used for the research of breast cancer[1].

• Target Antigen:

  Estrogen Receptor/ERR

• Type:

  Reference compound

• Related Pathways:

  Vitamin D Related/Nuclear Receptor

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/er-degrader-5.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=C(C=C(C=C1C)F)C)C(SC2=CC(F)=CC=C23)=C3OC4=CC=C(C=C4)/C=C/C(O)=O

• Molecular Weight:

  464.48

• References & Citations:

  [1]Lu Y, et, al. Design, synthesis and biological evaluation of fluorinated selective estrogen receptor degraders (FSERDs) --- A promising strategy for advanced ER positive breast cancer. Eur J Med Chem. 2023 May 5;253:115324.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported