ER degrader 1

• CAS Number:

  2667015-33-8

• UNSPSC Description:

  ER degrader 1 is a potent degrader of estrogen receptor (ER). The estrogen signaling system plays an important role in regulating cell growth, differentiation and apoptosis. ER degrader 1 has the potential for the research of cancer diseases (extracted from patent WO2021139756A1, compound 11)[1].

• Target Antigen:

  Estrogen Receptor/ERR

• Type:

  Reference compound

• Related Pathways:

  Vitamin D Related/Nuclear Receptor

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/er-degrader-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OCC(F)(F)CN1[C@@](C2=C(C=C(C=N2)N[C@@H]3CN(CC3)CCCF)F)([H])C4=C(C[C@H]1C)C=C5C(OCO5)=C4

• Molecular Weight:

  524.55

• References & Citations:

  [1]Fanglong Yang, et al. Tricyclic tetrahydroisoquinoline derivatives, their preparation methods and their application in medicine. Patent WO2021139756A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported