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ER degrader 11

CAT: 0931-T210553-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T210553-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2770911-29-8
Target
Estrogen Receptor/ERR
Related Pathways
Endocrinology/Hormones
Bioactivity
ER degrader 11 (Compound 5) is an orally active, brain-penetrant, and selective estrogen receptor degrader, with an ERα IC50 of 1.6 nM. It holds potential for research into breast cancer brain metastasis.
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C[C@H]1N(C23CC(C2)C3)[C@@H](C4=C(C1)C=5C(N4)=CC=CC5)C6=C(F)C=C(NC7CN(CCCF)C7)C=C6F
Molecular Formula
C29H33F3N4
Molecular Weight
494.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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