ER degrader 4

ER degrader 4

• CAS Number: 2913192-39-7
• UNSPSC Description: ER degrader 4 is a selective and orally active estrogen receptor degrader. ER degrader 4 has anti-tumor activity[1].
• Target Antigen: Estrogen Receptor/ERR
• Type: Reference compound
• Related Pathways: Vitamin D Related/Nuclear Receptor
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/er-degrader-4.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=C(C=C(C=C1)C)C)C(SC2=CC(F)=CC=C23)=C3OC4=CC=C(C=C4)/C=C/C(O)=O
• Molecular Weight: 446.49
• References & Citations: [1]Lu Y, et al. Design, synthesis and biological evaluation of fluorinated selective estrogen receptor degraders (FSERDs) --- A promising strategy for advanced ER positive breast cancer. Eur J Med Chem. 2023 May 5;253:115324.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported