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ER degrader 4

CAT: 0804-HY-149969Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149969Size:1 Each
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Description
ER degrader 4 is a selective and orally active estrogen receptor degrader. ER degrader 4 has anti-tumor activity[1].
CAS Number
2913192-39-7
UNSPSC
12352005
Target
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/er-degrader-4.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C=C(C=C1)C)C)C(SC2=CC(F)=CC=C23)=C3OC4=CC=C(C=C4)/C=C/C(O)=O
Molecular Formula
C26H19FO4S
Molecular Weight
446.49
References & Citations
[1]Lu Y, et al. Design, synthesis and biological evaluation of fluorinated selective estrogen receptor degraders (FSERDs) --- A promising strategy for advanced ER positive breast cancer. Eur J Med Chem. 2023 May 5;253:115324.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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