NF-κB-IN-3

• UNSPSC Description:

  NF-κB-IN-3 (Compound 2) is a NF-κB inhibitor with an IC50 of 0.70 µM. NF-κB-IN-3 can be used as an antitumor agent[1].

• Target Antigen:

  NF-κB

• Type:

  Reference compound

• Related Pathways:

  NF-κB

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/nf-κb-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1CCC2=CC=CC=C2N1C(C3=CC=CC(Cl)=C3)=O)NC4=CC=CC=C4C(F)(F)F

• Molecular Weight:

  458.86

• References & Citations:

  [1]Sim S, et al. Design, synthesis, and biological evaluation of potent 1,2,3,4-tetrahydroisoquinoline derivatives as anticancer agents targeting NF-κB signaling pathway. Bioorg Med Chem. 2021 Sep 15;46:116371.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1873311-82-0