NF-κB-IN-14

CAT: 0931-T208821-01Size: 10 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T208821-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

3019972-01-8

Target

NF-κB, TLR

Related Pathways

Immunology/Inflammation, NF-κB

Bioactivity

NF-κB-IN-14 (compound 5e) inhibits nitric oxide production in macrophages induced by LPS, with an IC50 of 6.4 μM. It disrupts the interaction between TLR4 and MyD88 proteins, thereby inhibiting the NF-κB signaling pathway. Additionally, NF-κB-IN-14 reduces ear edema and inflammation in a mouse model of atopic dermatitis.

Smiles

C(/C=C/C1=CC=C(C)C=C1)N2C=3C(N=C2)=C(Cl)N=C(Cl)N3

Molecular Formula

C15H12Cl2N4

Molecular Weight

319.19

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Related Products

Catalog	Name
T89612-01	NF-κB-IN-17
T62060-01	NF-κB-IN-5
T78750-01	NF-κB-IN-10
T209749-01	NF-κB-IN-16
T205560-01	NF-κB-IN-19
T79671-01	NF-κB-IN-11
T74799-01	NF-κB-IN-8
T209424-01	NF-κB-IN-15
T204218-01	NF-κB-IN-18
T62875-01	NF-κB-IN-3

Alternative Products

Catalog	Name
HY-162004	NF-κB-IN-14
60614	NF-κB Reporter Kit (NF-κB Signaling Pathway)
BA8604-1	NF-κB-IN-1
HY-144765-01	NF-κB-IN-4
HY-175833	NF-κB-IN-20
HY-158156	NF-κB-IN-16
HY-144744	NF-κB-IN-3
HY-149838	NF-κB-IN-9
HY-149248	NF-κB-IN-8
HY-149580	NF-κB-IN-12

NF-κB-IN-14

Related Products

Alternative Products

Popular Products