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NF-κB-IN-12

CAT: 0804-HY-149580Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149580Size:1 Each
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Description
NF-κB-IN-12 (compound 3h) is a potent NF-κB inhibitor, with an IC50 of 1.02 μM. NF-κB-IN-12 can be used for acute lung injury research[1].
UNSPSC
12352005
Target
NF-κB
Type
Reference compound
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nf-κb-in-12.html
Solubility
10 mM in DMSO
Smiles
O=C(N1N=CC(C2=CC=C(S(=O)(C3=CC=C(O)C=C3)=O)C=C2)C1C4=CC=C(OC)C=C4)C5=CN6C(C(NC)=NC=C6)=N5
Molecular Formula
C30H26N6O5S
Molecular Weight
582.63
References & Citations
[1]Zang B, et al. Synthesis and protective effect of pyrazole conjugated imidazo[1,2-a]pyrazine derivatives against acute lung injury in sepsis rats via attenuation of NF-κB, oxidative stress, and apoptosis. Acta Pharm. 2023 Sep 14;73 (3) :341-362.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

CatalogName
GTR19230847-01NF-κB-IN-12
sc-514451NFκB p65 (A-12)
sc-514451 XNFκB p65 (A-12) X
sc-514451 ACNFκB p65 (A-12) AC
sc-514451 PENFκB p65 (A-12) PE
sc-514451 FITCNFκB p65 (A-12) FITC
sc-514451 HRPNFκB p65 (A-12) HRP
sc-514451 AF546NFκB p65 (A-12) Alexa Fluor® 546
sc-514451 AF790NFκB p65 (A-12) Alexa Fluor® 790
sc-514451 AF680NFκB p65 (A-12) Alexa Fluor® 680

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